Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23850522 | 0.96 | MEN1 (0.45) | MEN1GLAKMT2ANPSR1TNF | |
| SCHEMBL29903004 | 0.89 | CNR2 (0.43) | MEN1GLAKMT2ATNFEPHX2 | |
| SCHEMBL23852583 | 0.89 | TNF (0.54) | TNFEPHX2CNR2GAA | |
| SCHEMBL29225350 | 0.87 | EPHX2 (0.44) | EPHX2CNR2KDM4EMAPTTSHR | |
| SCHEMBL23852674 | 0.84 | TNF (0.50) | TNFEPHX2CNR2ALDH1A1 | |
| SCHEMBL3024871 | 0.84 | EPHX2 (0.42) | TNFEPHX2CNR2KDM4EMAPT | |
| SCHEMBL30829444 | 0.83 | TSHR (0.46) | EPHX2KDM4EMAPTTSHRRAB9A | |
| SCHEMBL29225365 | 0.83 | TSHR (0.46) | EPHX2KDM4EMAPTTSHRNPC1 | |
| SCHEMBL3016395 | 0.81 | EPHX2 (0.44) | EPHX2KDM4EMAPTTSHRNPC1 | |
| SCHEMBL13541632 | 0.80 | TSHR (0.48) | EPHX2MAPTTSHRSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883931-A1 | HETEROCYCLIC COMPOUNDS AND MEDICAL USE THEREOF | Fondazione Telethon (IT) | 2021-09-29 | — | — | EP | disclosed |