Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1693314 | 1.00 | DPP4 (0.46) | DPP4GAAHPGDKDM4EPKM | |
| SCHEMBL28646412 | 0.88 | DPP4 (0.46) | DPP4GAAHPGDKDM4EPKM | |
| SCHEMBL23849943 | 0.88 | DPP4 (0.46) | DPP4GAAHPGDKDM4EPKM | |
| SCHEMBL7350839 | 0.86 | HPGD (0.46) | DPP4GAAHPGDKDM4EPKM | |
| SCHEMBL21564360 | 0.85 | HPGD (0.45) | DPP4GAAHPGDKDM4EPKM | |
| SCHEMBL31082333 | 0.85 | HPGD (0.45) | DPP4GAAHPGDKDM4EPKM | |
| SCHEMBL4596204 | 0.85 | HPGD (0.45) | DPP4GAAHPGDKDM4EPKM | |
| SCHEMBL18099946 | 0.85 | KDM4E (0.49) | DPP4HPGDKDM4EPKMRECQL | |
| SCHEMBL27915354 | 0.85 | KDM4E (0.49) | DPP4HPGDKDM4EPKMRECQL | |
| SCHEMBL5322912 | 0.84 | HPGD (0.44) | DPP4GAAHPGDKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883647-A1 | C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF | Zikani Therapeutics, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |