Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23853977 | 0.83 | BCHE (0.33) | ALDH1A1LMNA | |
| SCHEMBL23852846 | 0.80 | HTR2C (0.31) | HSD11B1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL23850110 | 0.80 | TEAD1 (0.38) | DRD4CHRM4ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL23853475 | 0.79 | HTR2C (0.37) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL896227 | 0.78 | — | — | |
| SCHEMBL24210637 | 0.78 | DRD4 (0.35) | DRD4CHRM4ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL23850101 | 0.78 | USP30 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL23853479 | 0.78 | USP30 (0.34) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21064763 | 0.78 | — | — | |
| SCHEMBL10207361 | 0.77 | DRD4 (0.34) | DRD4ALDH1A1LMNAMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883938-A1 | INHIBITORS OF ARGINASE | Praxis Biotech LLC (US) | 2021-09-29 | — | — | EP | disclosed |