Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 6/20 | 0.67 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 2/20 | 0.51 |
| ▸ | WDR5 | P61964 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587562 | 1.00 | ERAP1 (0.67) | ERAP1ERAP2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL31587915 | 0.92 | ERAP1 (0.75) | ERAP1ERAP2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL31588233 | 0.92 | ERAP1 (0.77) | ERAP1ERAP2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL23850850 | 0.92 | ERAP1 (0.75) | ERAP1ERAP2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL23852112 | 0.92 | ERAP1 (0.77) | ERAP1ERAP2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL23850707 | 0.89 | ERAP1 (0.70) | ERAP1ERAP2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL31587816 | 0.89 | ERAP1 (0.70) | ERAP1ERAP2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL23850731 | 0.87 | ERAP1 (0.85) | ERAP1ERAP2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL23851151 | 0.86 | ERAP1 (0.86) | ERAP1ERAP2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL23850325 | 0.84 | ERAP1 (0.80) | ERAP1ERAP2L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12485169-B2 | Compounds | Grey Wolf Therapeutics Limited (GB) | 2025-12-02 | — | — | US | disclosed |
| US-20230064417-A1 | COMPOUNDS | Grey Wolf Therapeutics Limited (GB) | 2023-03-02 | — | — | US | disclosed |
| EP-3883650-A1 | COMPOUNDS | Grey Wolf Therapeutics Limited (GB) | 2021-09-29 | — | — | EP | disclosed |
| CN-113056305-A | Compound (I) | 格雷沃尔夫治疗有限公司 | 2021-06-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230064417-A1 | COMPOUNDS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HRH4, CBR3 | ERAP1 4866/4885ERAP2 4830/4885L3MBTL1 3697/4885 |
| US-12485169-B2 | Compounds | SLC10A1, VHL, CFTR | ERAP1 3893/4885ERAP2 3098/4885L3MBTL1 4696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.