⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534 | 0.75 | — | — | |
| SCHEMBL14941161 | 0.71 | — | — | |
| SCHEMBL3598231 | 0.71 | — | — | |
| SCHEMBL10931857 | 0.71 | — | — | |
| SCHEMBL10788422 | 0.65 | — | — | |
| SCHEMBL2264879 | 0.65 | — | — | |
| SCHEMBL8633356 | 0.65 | — | — | |
| SCHEMBL93745 | 0.65 | — | — | |
| SCHEMBL6707281 | 0.65 | — | — | |
| SCHEMBL11054393 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794284-B1 | METHOD FOR CHONDROCYTE EXPANSION WITH PHENOTYPE RETENTION | ISTO TECH INC (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-2201099-B1 | METHOD FOR CHONDROCYTE EXPANSION WITH PHENOTYPE RETENTION | ISTO TECHNOLOGIES INC (US) | 2014-11-19 | — | — | EP | disclosed |
| US-8017394-B2 | Propagating cartilage tissues from chrondrocytes resistant to immune mediated xenograft rejection | ISTO TECHNOLOGIES, INC. (US) | 2011-09-13 | — | — | US | disclosed |
| US-20080081369-A1 | Method for Chondrocyte Expansion with Phenotype Retention | ISTO TECHNOLOGIES, INC. (US) | 2008-04-03 | — | — | US | disclosed |
| US-7273756-B2 | Method for chondrocyte expansion with phenotype retention | ISTO TECHNOLOGIES, INC. (US) | 2007-09-25 | — | — | US | disclosed |
| US-20060073588-A1 | Method for chondrocyte expansion with phenotype retention | ISTO TECHNOLOGIES, INC. | 2006-04-06 | — | — | US | disclosed |
| EP-0342962-B1 | Peptides having T cell helper activity | IMMUNOBIOLOGY RES INST INC (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0602004-A1 | Peptides having T cell helper activity | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1994-06-15 | — | — | EP | disclosed |
| EP-0602003-A1 | Peptides having T cell helper activity | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5298490-A | Tetra and penta-peptides useful in regulating the immune system | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0342962-A2 | Peptides having T cell helper activity | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1989-11-23 | — | — | EP | disclosed |