Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716874 | 0.80 | MEN1 (0.38) | CHKARAB9ALMNAMEN1MAPT | |
| SCHEMBL10637518 | 0.76 | CHKA (0.42) | CHKARAB9ALMNAF2PRSS1 | |
| SCHEMBL13561372 | 0.70 | CHKA (0.49) | CHKARAB9A | |
| SCHEMBL6270092 | 0.69 | — | — | |
| SCHEMBL9329770 | 0.67 | — | — | |
| SCHEMBL11471371 | 0.67 | — | — | |
| Bromide SCHEMBL5900297 | 0.67 | BCHE (0.42) | — | |
| Hydrochloric Acid SCHEMBL2207314 | 0.67 | CHRNA7 (0.38) | — | |
| SCHEMBL12763760 | 0.67 | CHKA (0.42) | CHKARAB9ALMNAF2PRSS1 | |
| SCHEMBL21005518 | 0.65 | CHKA (0.45) | CHKARAB9ALMNAF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021191882-A1 | ANTIMALARIAL AGENT, METHODS AND USES THEREOF | UNIVERSIDADE DO MINHO (PT) | 2021-09-30 | — | — | WO | disclosed |