Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23856050 | 0.85 | MAPT (0.34) | HTR2CHTR2BALDH1A1TP53TSHR | |
| SCHEMBL23856051 | 0.81 | HTR2C (0.34) | HTR2CHTR2BALDH1A1TP53TSHR | |
| SCHEMBL24353419 | 0.80 | HTR2C (0.36) | HTR2CHTR2BALDH1A1TSHR | |
| SCHEMBL23856054 | 0.79 | HTR2C (0.33) | HTR2CHTR2BALDH1A1TP53TSHR | |
| SCHEMBL23856060 | 0.78 | HTR2C (0.32) | HTR2CHTR2B | |
| SCHEMBL28612754 | 0.78 | HTR2C (0.35) | HTR2CHTR2B | |
| SCHEMBL28629203 | 0.77 | HTR2C (0.37) | HTR2CHTR2B | |
| SCHEMBL28631801 | 0.77 | HTR2C (0.37) | HTR2CHTR2BALDH1A1 | |
| SCHEMBL23866934 | 0.76 | HTR2C (0.33) | HTR2CHTR2B | |
| SCHEMBL23748310 | 0.76 | HTR2C (0.34) | HTR2CHTR2BALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021191872-A1 | HETEROARYL-SUBSTITUTED MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | Janssen Biopharma, Inc. (US) | 2021-09-30 | — | — | WO | disclosed |