Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL23856809 | 0.93 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL21409398 | 0.92 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL21428570 | 0.92 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL21409401 | 0.92 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL30393246 | 0.92 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL21820193 | 0.85 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL23084922 | 0.85 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL21820190 | 0.85 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL23856765 | 0.84 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL21883278 | 0.84 | KCNH2 (0.52) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126855-B1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | HOFFMANN LA ROCHE (CH) | 2024-04-24 | — | — | EP | disclosed |
| EP-4126855-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-02-08 | — | — | EP | disclosed |
| WO-2021190727-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2021-09-30 | — | — | WO | disclosed |