Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17734356 | 0.80 | EZH2 (0.57) | EZH2 | |
| SCHEMBL17136159 | 0.77 | EZH2 (0.84) | EZH2 | |
| SCHEMBL13277481 | 0.77 | EZH2 (0.77) | EZH2 | |
| SCHEMBL13276887 | 0.76 | EZH2 (1.00) | EZH2 | |
| SCHEMBL13446317 | 0.76 | EZH2 (0.80) | EZH2 | |
| SCHEMBL17136158 | 0.76 | EZH2 (0.81) | EZH2 | |
| SCHEMBL17136198 | 0.75 | EZH2 (0.92) | EZH2 | |
| SCHEMBL13277024 | 0.75 | EZH2 (1.00) | EZH2 | |
| SCHEMBL19503505 | 0.75 | EZH2 (0.81) | EZH2 | |
| SCHEMBL17734421 | 0.74 | EZH2 (0.55) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885343-A1 | INDOLE COMPOUNDS AS EZH2 INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |