Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28350435 | 0.87 | MAPT (0.58) | CLCN2AKR1C3AKR1C2FABP4MEN1 | |
| SCHEMBL15119809 | 0.85 | MAPT (0.65) | KMT2ALMNACYP1A2PTGS2TDP1 | |
| SCHEMBL8574363 | 0.84 | POLB (0.53) | CLCN2FABP4KMT2ATDP1MAPT | |
| SCHEMBL12333926 | 0.84 | CLCN2 (0.41) | CLCN2KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL22385143 | 0.82 | MAPT (0.53) | CLCN2AKR1C3AKR1C2FABP4MEN1 | |
| SCHEMBL14344990 | 0.82 | POLB (0.44) | CLCN2KMT2ALMNAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL28447296 | 0.82 | POLB (0.52) | CLCN2FABP4KMT2ATDP1MAPT | |
| SCHEMBL11463051 | 0.82 | CLCN2 (0.40) | CLCN2AKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL18287256 | 0.80 | MEN1 (0.61) | CLCN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL107161 | 0.79 | MEN1 (0.40) | CLCN2MEN1KMT2APTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |