Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SQLE | Q14534 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103585 | 0.85 | KMT2A (0.53) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL3084553 | 0.85 | KMT2A (0.53) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL3103575 | 0.85 | KMT2A (0.53) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL3092262 | 0.85 | KMT2A (0.53) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL3092254 | 0.85 | KMT2A (0.53) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL3084555 | 0.85 | KMT2A (0.53) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL11849974 | 0.83 | TRPV1 (0.58) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL11855432 | 0.83 | KMT2A (0.52) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL11855421 | 0.83 | KMT2A (0.52) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL11849987 | 0.83 | TRPV1 (0.58) | KMT2ASQLEMAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436451-B1 | SPHINGOSINE KINASE INHIBITOR AMIDOXIME PRODRUGS | UNIV VIRGINIA PATENT FOUNDATION (US) | 2021-09-29 | — | — | EP | disclosed |