Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.60 |
| ▸ | JAK2 | O60674 | 8/20 | 0.60 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21313073 | 0.90 | NTRK1 (0.70) | NTRK1JAK2 | |
| SCHEMBL20119110 | 0.90 | NTRK1 (0.70) | NTRK1JAK2 | |
| SCHEMBL21319483 | 0.88 | NTRK1 (0.62) | NTRK1JAK2 | |
| SCHEMBL21319514 | 0.86 | NTRK1 (0.56) | NTRK1JAK2NTRK3 | |
| SCHEMBL21313050 | 0.85 | NTRK1 (0.64) | NTRK1JAK2 | |
| SCHEMBL20119341 | 0.85 | NTRK1 (0.64) | NTRK1JAK2 | |
| SCHEMBL20119354 | 0.85 | NTRK1 (0.61) | NTRK1JAK2NTRK3 | |
| SCHEMBL20119356 | 0.85 | NTRK1 (0.69) | NTRK1JAK2 | |
| SCHEMBL20119353 | 0.85 | NTRK1 (0.69) | NTRK1JAK2 | |
| SCHEMBL20119164 | 0.84 | NTRK1 (0.70) | NTRK1JAK2NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3533796-B1 | AMINO PYRAZOLOPYRIMIDINE COMPOUND USED AS NEUROTROPHIC FACTOR TYROSINE KINASE RECEPTOR INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2021-09-29 | — | — | EP | disclosed |