Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21016377 | 0.70 | RPS6KA5 (0.35) | RPS6KA5TRPV1ROCK1TP53MDM2 | |
| SCHEMBL23865470 | 0.64 | ROCK1 (0.39) | RPS6KA5TRPV1ROCK1 | |
| SCHEMBL30463156 | 0.63 | QPCT (0.45) | RPS6KA5TP53MDM2 | |
| SCHEMBL28183425 | 0.63 | QPCT (0.45) | RPS6KA5TP53MDM2 | |
| SCHEMBL28183428 | 0.63 | QPCT (0.45) | RPS6KA5TP53MDM2 | |
| SCHEMBL20677047 | 0.63 | HDAC6 (0.47) | TP53MDM2 | |
| SCHEMBL19402044 | 0.63 | HDAC6 (0.47) | TP53MDM2 | |
| SCHEMBL1427771 | 0.63 | TRPV1 (0.45) | RPS6KA5TRPV1 | |
| SCHEMBL28477218 | 0.63 | RPS6KA5 (0.38) | RPS6KA5TRPV1ROCK1 | |
| SCHEMBL12502444 | 0.63 | PTPN1 (0.38) | IDO1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885344-A2 | PYRIMIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | InventisBio Co., Ltd. (CN) | 2021-09-29 | — | — | EP | disclosed |