Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361707 | 0.76 | TSHR (0.33) | TSHR | |
| SCHEMBL29701224 | 0.74 | TSHR (0.30) | TSHR | |
| SCHEMBL20942324 | 0.71 | HRH3 (0.35) | — | |
| SCHEMBL29701240 | 0.70 | — | — | |
| SCHEMBL24310949 | 0.70 | TSHR (0.47) | TSHR | |
| SCHEMBL1176768 | 0.70 | TSHR (0.47) | TSHR | |
| SCHEMBL20942316 | 0.69 | HTR2A (0.35) | — | |
| SCHEMBL22145022 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL1184612 | 0.69 | TSHR (0.46) | TSHR | |
| SCHEMBL26371301 | 0.68 | PARP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416966-B1 | PROCESS FOR THE PREPARATION OF [7-[[4-PHENYL-5-ALKOXYCARBONYL-2-THIAZOL-2-YL-1,4-DIHYDROPYRIMIDIN-6-YL]METHYL]-3-OXO-5,6,8,8A-TETRAHYDRO-1H-IMIDAZO[1,5-A]PYRAZIN-2-YL]ALKYL CARBOXYLIC ACIDS | HOFFMANN LA ROCHE (CH) | 2021-09-29 | — | — | EP | disclosed |