Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410795 | 1.00 | CTSC (0.45) | CTSCDPP7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL15572634 | 1.00 | CTSC (0.45) | CTSCDPP7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27042548 | 0.83 | CTSC (0.41) | CTSCDPP7ACACBSMN1; SMN2SSTR4 | |
| SCHEMBL27042542 | 0.83 | CTSC (0.41) | CTSCDPP7ACACBSMN1; SMN2SSTR4 | |
| SCHEMBL1442858 | 0.80 | CTSC (0.40) | CTSCCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL27410797 | 0.80 | CTSC (0.40) | CTSCCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL1442856 | 0.80 | CTSC (0.40) | CTSCCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL23866604 | 0.79 | CTSC (0.40) | CTSCACACBCD274 | |
| SCHEMBL25039138 | 0.77 | DPP7 (0.46) | CTSCDPP7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL20418559 | 0.77 | DPP7 (0.46) | CTSCDPP7CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300940-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300940-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | TLR7, TLR8, TLR9 | CTSC 1498/4885DPP7 461/4885CHRNB2 2068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.