Flavonol

Flavonol

SCHEMBL2386663

O=c1c(O)c(-c2ccccc2)oc2ccccc12.[Zn]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.97
MEN1 O00255 10/20 0.97
KMT2A Q03164 10/20 0.97
CYP3A4 P08684 9/20 0.97
TP53 P04637 7/20 0.97
MAPK1 P28482 6/20 0.97
ALOX15 P16050 5/20 0.97
LMNA P02545 4/20 0.97
CA12 O43570 1/20 0.97
CA1 P00915 1/20 0.97
CA2 P00918 1/20 0.97
ABCB1 P08183 1/20 0.97
CALM1 P0DP23 1/20 0.97
AR P10275 1/20 0.97
PKM P14618 1/20 0.97
CYP1B1 Q16678 1/20 0.97
CA9 Q16790 1/20 0.97
HSD17B10 Q99714 7/20 0.79
HPGD P15428 5/20 0.79
ALDH1A1 P00352 4/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flavonol SCHEMBL1679068 0.98 KDM4E (1.00) KDM4EMEN1KMT2ACYP3A4TP53
Flavonol SCHEMBL20246 0.98 KDM4E (1.00) KDM4EMEN1KMT2ACYP3A4TP53
Flavonol SCHEMBL29433939 0.98 KDM4E (1.00) KDM4EMEN1KMT2ACYP3A4TP53
Flavonol SCHEMBL27822085 0.97 KDM4E (0.97) KDM4EMEN1KMT2ACYP3A4TP53
Flavonol SCHEMBL28090288 0.97 KDM4E (0.97) KDM4EMEN1KMT2ACYP3A4TP53
Flavonol SCHEMBL31570209 0.97 KDM4E (0.97) KDM4EMEN1KMT2ACYP3A4TP53
Flavonol SCHEMBL31328341 0.97 KDM4E (0.97) KDM4EMEN1KMT2ACYP3A4TP53
Flavonol SCHEMBL21874432 0.97 KDM4E (0.97) KDM4EMEN1KMT2ACYP3A4TP53
Flavonol SCHEMBL21874433 0.97 KDM4E (0.97) KDM4EMEN1KMT2ACYP3A4TP53
Flavonol SCHEMBL28055468 0.97 KDM4E (0.97) KDM4EMEN1KMT2ACYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1935919-B1 POLYMER CONTAINING SULFO GROUP AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE POLYMER YAMAMOTO CHEMICALS INC (JP) 2012-09-05 EP disclosed
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-8012608-B2 Polymer containing sulfo group and organic electroluminescent element containing the polymer Yamamoto Chemcials, Inc. (JP) 2011-09-06 US disclosed
US-20090230851-A1 Polymer Containing Sulfo Group and Organic Electroluminescent Element Containing the Polymer MITSUI CHEMICALS, INC. (JP) 2009-09-17 US disclosed
EP-1935919-A1 POLYMER CONTAINING SULFO GROUP AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE POLYMER Mitsui Chemicals, Inc. (JP) 2008-06-25 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-20050240061-A1 Functional thin film JAPAN SCIENCE AND TECHNOLOGY AGENCY 2005-10-27 US disclosed
US-6929870-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2005-08-16 US disclosed
US-20050074631-A1 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2005-04-07 US disclosed
EP-1493796-A1 FUNCTIONAL THIN FILM Japan Science and Technology Agency (JP) 2005-01-05 EP disclosed
US-20030087126-A1 Hydrocarbon compound, material for organic electroluminescent element and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2003-05-08 US disclosed
EP-1221434-A1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT Mitsui Chemicals, Inc. (JP) 2002-07-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050240061-A1 Functional thin film H1-10, H1-0, H1-2 KDM4E 2385/4885MEN1 1195/4885KMT2A 647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.