Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23870268 | 0.89 | HTR2A (0.32) | — | |
| SCHEMBL12327553 | 0.79 | PARP1 (0.39) | PARP1DAO | |
| SCHEMBL28357979 | 0.79 | PARP1 (0.39) | PARP1DAOERN1 | |
| SCHEMBL8403384 | 0.78 | PARP1 (0.42) | PARP1DAO | |
| SCHEMBL25166194 | 0.76 | PARP1 (0.37) | PARP1DAOERN1 | |
| SCHEMBL5538999 | 0.76 | PARP1 (0.41) | PARP1DAO | |
| SCHEMBL5539003 | 0.76 | ESR1 (0.44) | PARP1DAOERN1 | |
| SCHEMBL23729377 | 0.76 | PARP1 (0.37) | PARP1DAO | |
| SCHEMBL28330119 | 0.76 | PARP1 (0.37) | PARP1DAO | |
| SCHEMBL27051609 | 0.76 | PARP1 (0.34) | PARP1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195183-A1 | COMPOSITIONS AND METHODS FOR INHIBITING PROTEIN EMBRYONIC ECTODERM DEVELOPMENT ACTIVITY AND TREATING DISEASE | EXO THERAPEUTICS, INC. (US) | 2021-09-30 | — | — | WO | disclosed |
| CN-108329285-B | Method for synthesizing 2, 3-dihydrobenzofuran compound | 武汉大学 | 2019-12-10 | — | — | CN | disclosed |