SCHEMBL23871017

SCHEMBL23871017

CSc1ccc(C(C)/C=C\c2cc(C)c(OC(C)(C)CO)c(C)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 4/20 0.46
PPARG P37231 3/20 0.46
PPARD Q03181 3/20 0.46
CYP1A1 P04798 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP1B1 Q16678 2/20 0.33
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
HTT P42858 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
RCE1 Q9Y256 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23871140 1.00 PPARA (0.46) PPARAPPARGPPARDCYP1A1CYP1A2
SCHEMBL23158203 0.88 PPARA (0.46) PPARAPPARGPPARDCYP1A1CYP1A2
SCHEMBL23143285 0.88 PPARA (0.46) PPARAPPARGPPARDCYP1A1CYP1A2
SCHEMBL23143284 0.88 PPARA (0.46) PPARAPPARGPPARDCYP1A1CYP1A2
SCHEMBL24658508 0.84 PPARA (0.45) PPARAPPARGPPARDCYP1A1CYP1A2
SCHEMBL23871018 0.83 PPARA (0.67) PPARAPPARGPPARD
SCHEMBL23870994 0.83 PPARA (0.67) PPARAPPARGPPARD
SCHEMBL24884305 0.82 PPARA (0.48) PPARAPPARGPPARDCYP1A1CYP1A2
SCHEMBL23158209 0.80 PPARA (0.47) PPARAPPARGPPARDCYP1A1CYP1A2
SCHEMBL23158224 0.80 PPARA (0.47) PPARAPPARGPPARDCYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230278952-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2023-09-07 US disclosed
US-20230008367-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES ABIONYX PHARMA SA (FR) 2023-01-12 US disclosed
US-20220363632-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2022-11-17 US disclosed
US-20210300890-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2021-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278952-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARA 94/4885PPARG 71/4885PPARD 332/4885
US-20210300890-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARA 94/4885PPARG 71/4885PPARD 332/4885
US-20230008367-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES SLC10A1, CPT1A, CES1 PPARA 27/4885PPARG 42/4885PPARD 144/4885
US-20220363632-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARA 94/4885PPARG 71/4885PPARD 332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.