Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 8/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21105824 | 0.91 | KDM4E (0.43) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL861505 | 0.91 | KDM4E (0.43) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL11956477 | 0.91 | KDM4E (0.43) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL21925758 | 0.90 | GLP1R (0.39) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL26706506 | 0.88 | MEN1 (0.44) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL26706574 | 0.88 | MEN1 (0.44) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL16543781 | 0.87 | KDM4E (0.40) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL26020269 | 0.87 | KDM4E (0.44) | MEN1KMT2AKDM4ETDP1GLP1R | |
| SCHEMBL26818481 | 0.87 | MEN1 (0.37) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL26865995 | 0.87 | MEN1 (0.41) | MEN1KMT2AKDM4EPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021193983-A2 | QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-09-30 | — | — | WO | disclosed |