Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23609758 | 0.82 | EGLN3 (0.46) | EGLN3KDM4EALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL23875663 | 0.81 | — | — | |
| SCHEMBL22212153 | 0.77 | — | — | |
| SCHEMBL4022901 | 0.76 | — | — | |
| SCHEMBL24134598 | 0.76 | EGLN3 (0.41) | EGLN3KDM4EALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL21886558 | 0.74 | EGLN3 (0.47) | EGLN3KDM4EALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL20988256 | 0.72 | EGLN3 (0.41) | EGLN3KDM4EALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL20445070 | 0.72 | EGLN3 (0.53) | EGLN3MAPTMEN1KMT2A | |
| SCHEMBL19868522 | 0.72 | EGLN3 (0.41) | EGLN3KDM4EALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL21850758 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195346-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-09-30 | — | — | WO | disclosed |