Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.54 |
| ▸ | CDK2 | P24941 | 5/20 | 0.45 |
| ▸ | CDK4 | P11802 | 4/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 4/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571475 | 0.85 | PIK3CG (0.52) | PIK3CAPIK3CDPIK3CBPIK3CGCDK2 | |
| SCHEMBL30476425 | 0.85 | PIK3CG (0.52) | PIK3CAPIK3CDPIK3CBPIK3CGCDK2 | |
| SCHEMBL18616748 | 0.82 | PIK3CA (0.61) | PIK3CAPIK3CDPIK3CBPIK3CGCDK2 | |
| SCHEMBL3491367 | 0.79 | PIK3CA (0.55) | PIK3CAPIK3CDPIK3CBPIK3CGLMNA | |
| SCHEMBL571448 | 0.77 | PIK3CG (0.71) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29011650 | 0.76 | PIK3CA (0.55) | PIK3CAPIK3CDPIK3CBPIK3CGLMNA | |
| SCHEMBL16045646 | 0.72 | PIK3CA (0.48) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30500997 | 0.72 | PIK3CA (0.51) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL15801542 | 0.72 | PIK3CA (0.51) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL10145051 | 0.71 | JAK2 (0.45) | CDK2CDK4CCNE1JAK2COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021189143-A1 | STABLE HEAVY ISOTOPES IN AMIDE FUNCTIONAL GROUPS AND USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2021-09-30 | — | — | WO | disclosed |