Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23876873 | 0.93 | IGF1R (0.49) | IGF1RNAMPTCA1CA2ALDH1A1 | |
| SCHEMBL23876526 | 0.91 | IGF1R (0.51) | IGF1RNAMPTCA1CA2ALDH1A1 | |
| SCHEMBL23876879 | 0.88 | MAPT (0.41) | MAPTPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL23876536 | 0.85 | IGF1R (0.54) | IGF1RNAMPTCA1CA2MAPT | |
| SCHEMBL30810306 | 0.82 | IGF1R (0.51) | IGF1RNAMPTCA1CA2ALDH1A1 | |
| SCHEMBL25004233 | 0.82 | IGF1R (0.51) | IGF1RNAMPTCA1CA2ALDH1A1 | |
| SCHEMBL19889032 | 0.80 | NAMPT (0.61) | NAMPTCA1CA2MAPTPOLB | |
| SCHEMBL1626418 | 0.79 | IGF1R (0.51) | IGF1RNAMPTCA1CA2MAPT | |
| SCHEMBL1626696 | 0.76 | IGF1R (0.47) | IGF1RNAMPTCA1CA2ALDH1A1 | |
| SCHEMBL13892876 | 0.72 | NAMPT (0.56) | IGF1RNAMPTCA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023012820-A1 | A PROCESS FOR THE PREPARATION OF GRAPIPRANT AND ITS INTERMEDIATES | ZENFOLD SUSTAINABLE TECHNOLOGIES PRIVATE LIMITED (IN) | 2023-02-09 | — | — | WO | disclosed |
| US-20210300921-A1 | EP4 INHIBITORS AND SYNTHESIS THEREOF | ASKAT INC. (JP) | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300921-A1 | EP4 INHIBITORS AND SYNTHESIS THEREOF | PTGER4, EPB41, CDK4 | IGF1R 4247/4885NAMPT 1024/4885CA1 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.