Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | PGK1 | P00558 | 4/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ILK | Q13418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24688290 | 0.82 | KDM4E (0.57) | KDM4EMAPK1NPSR1L3MBTL1CYP1A1 | |
| SCHEMBL12141863 | 0.81 | KDM4E (0.69) | KDM4EMAPK1NPSR1L3MBTL1PGK1 | |
| SCHEMBL13150847 | 0.76 | MAPT (0.53) | KDM4EMAPK1L3MBTL1CYP1A2MEN1 | |
| SCHEMBL26534307 | 0.76 | MAPT (0.47) | KDM4EMAPK1NPSR1L3MBTL1CYP1A1 | |
| SCHEMBL11695334 | 0.74 | KDM4E (0.52) | KDM4EMAPK1NPSR1L3MBTL1CYP1A1 | |
| SCHEMBL17014813 | 0.74 | KDM4E (0.70) | KDM4EMAPK1NPSR1L3MBTL1PGK1 | |
| SCHEMBL18721598 | 0.72 | KDM4E (0.43) | KDM4EMAPK1NPSR1L3MBTL1CYP1A2 | |
| SCHEMBL18721843 | 0.72 | TSHR (0.39) | KDM4ENPSR1CYP1A2ELANEPOLB | |
| SCHEMBL6312005 | 0.71 | TDP1 (0.58) | KDM4ENPSR1L3MBTL1MEN1POLB | |
| SCHEMBL11327423 | 0.69 | MAPT (0.47) | KDM4EMAPK1L3MBTL1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021194914-A1 | SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-09-30 | — | — | WO | disclosed |