Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.77 |
| ▸ | JAK3 | P52333 | 20/20 | 0.77 |
| ▸ | JAK1 | P23458 | 17/20 | 0.77 |
| ▸ | JAK2 | O60674 | 16/20 | 0.77 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.65 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22054141 | 1.00 | TYK2 (0.77) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24995476 | 1.00 | TYK2 (0.77) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24995475 | 0.93 | TYK2 (0.78) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL22054150 | 0.93 | TYK2 (0.78) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL23878880 | 0.93 | TYK2 (0.78) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL30227599 | 0.93 | TYK2 (0.78) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL22054143 | 0.91 | TYK2 (0.66) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL22054280 | 0.91 | TYK2 (0.78) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL23879055 | 0.91 | TYK2 (0.78) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24996734 | 0.91 | TYK2 (0.78) | TYK2JAK3JAK1JAK2P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003441-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-115925705-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-116003441-A | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115925705-A | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-111511738-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-01-20 | — | — | CN | disclosed |
| EP-3889152-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| EP-3889152-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |