Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405732 | 1.00 | TBXA2R (0.35) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276174 | 0.91 | TBXA2R (0.34) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276149 | 0.87 | TBXA2R (0.34) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276335 | 0.86 | FLT1 (0.38) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276178 | 0.83 | PTGER4 (0.38) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL28479847 | 0.81 | MAOB (0.35) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276163 | 0.81 | PTGER4 (0.39) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276143 | 0.79 | PTGER4 (0.39) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276142 | 0.79 | TBXA2R (0.37) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL22276145 | 0.79 | PTGER4 (0.37) | TBXA2RPTGER1PTGER4PTGFRPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889134-A1 | COMPOUND FOR INHIBITING PGE2/EP4 SIGNALING TRANSDUCTION INHIBITING, PREPARATION METHOD THEREFOR, AND MEDICAL USES THEREOF | Keythera (Suzhou) Pharmaceuticals Co. Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| EP-3889134-A1 | COMPOUND FOR INHIBITING PGE2/EP4 SIGNALING TRANSDUCTION INHIBITING, PREPARATION METHOD THEREFOR, AND MEDICAL USES THEREOF | Keythera (Suzhou) Pharmaceuticals Co. Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |