Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134755 | 0.84 | — | — | |
| SCHEMBL30631964 | 0.84 | — | — | |
| SCHEMBL30091824 | 0.82 | TSHR (0.94) | TSHRHSD17B10HPGDCYP3A4MAPK1 | |
| SCHEMBL31252200 | 0.82 | TSHR (0.94) | TSHRHSD17B10HPGDCYP3A4MAPK1 | |
| Ammonia Solution, Strong SCHEMBL29156113 | 0.82 | TSHR (0.94) | TSHRHSD17B10HPGDCYP3A4MAPK1 | |
| Hydrochloric Acid SCHEMBL9797291 | 0.82 | TSHR (0.94) | TSHRHSD17B10HPGDCYP3A4MAPK1 | |
| SCHEMBL5842280 | 0.82 | TSHR (0.94) | TSHRHSD17B10HPGDCYP3A4MAPK1 | |
| SCHEMBL31006506 | 0.82 | TSHR (0.94) | TSHRHSD17B10HPGDCYP3A4MAPK1 | |
| Phosphine SCHEMBL29064576 | 0.82 | TSHR (0.94) | TSHRHSD17B10HPGDCYP3A4MAPK1 | |
| Methane SCHEMBL28589037 | 0.82 | TSHR (0.94) | TSHRHSD17B10HPGDCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |