Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Dithiothreitol SCHEMBL23883129 | 1.00 | PTGS1 (0.55) | PTGS1SLC7A11LMNASLC1A1USP2 | |
| Cysteine SCHEMBL3396295 | 0.89 | PTGS1 (0.70) | PTGS1SLC7A11LMNASLC1A1USP2 | |
| Cysteine SCHEMBL3396289 | 0.89 | PTGS1 (0.70) | PTGS1SLC7A11LMNASLC1A1USP2 | |
| Cysteine SCHEMBL888041 | 0.83 | PTGS1 (0.73) | PTGS1SLC7A11LMNASLC1A1USP2 | |
| Cysteine SCHEMBL888042 | 0.83 | PTGS1 (0.73) | PTGS1SLC7A11LMNASLC1A1USP2 | |
| Cysteine SCHEMBL8660333 | 0.83 | PTGS1 (0.80) | PTGS1SLC7A11SLC1A1ENPEPANPEP | |
| Cysteine SCHEMBL8660332 | 0.83 | PTGS1 (0.80) | PTGS1SLC7A11SLC1A1ENPEPANPEP | |
| Dl-Dithiothreitol SCHEMBL28838774 | 0.83 | PTGS1 (0.80) | PTGS1SLC7A11SLC1A1ENPEPANPEP | |
| Cysteine SCHEMBL27658901 | 0.77 | PTGS1 (0.84) | PTGS1SLC7A11SLC1A1ENPEPANPEP | |
| Mannitol SCHEMBL9223735 | 0.76 | PTGS1 (0.67) | PTGS1SLC7A11LMNASLC1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021201202-A1 | ANALYSIS METHOD FOR IMPURITY MOLECULES IN COMPOSITION CONTAINING MULTI-SPECIFIC ANTIGEN-BINDING MOLECULES | 中外製薬株式会社 | 2021-10-07 | — | — | WO | claimed |
| WO-2021201202-A1 | ANALYSIS METHOD FOR IMPURITY MOLECULES IN COMPOSITION CONTAINING MULTI-SPECIFIC ANTIGEN-BINDING MOLECULES | 中外製薬株式会社 | 2021-10-07 | — | — | WO | disclosed |