Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23883321 | 1.00 | HDAC1 (0.50) | HDAC1LMNASMN1; SMN2HDAC8HDAC3 | |
| SCHEMBL23883257 | 0.90 | MAPT (0.61) | HDAC1LMNASMN1; SMN2HDAC8HDAC3 | |
| SCHEMBL23883258 | 0.90 | MAPT (0.61) | HDAC1LMNASMN1; SMN2HDAC8HDAC3 | |
| SCHEMBL22718808 | 0.87 | HDAC1 (0.53) | HDAC1HDAC8HDAC3HDAC11HDAC6 | |
| SCHEMBL23883383 | 0.87 | HDAC1 (0.53) | HDAC1HDAC8HDAC3HDAC11HDAC6 | |
| SCHEMBL26488662 | 0.85 | KMT2A (0.48) | HDAC1LMNASMN1; SMN2HDAC8HDAC3 | |
| SCHEMBL30373016 | 0.85 | KMT2A (0.48) | HDAC1LMNASMN1; SMN2HDAC8HDAC3 | |
| SCHEMBL23883311 | 0.82 | MAPT (0.47) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL23883301 | 0.82 | MAPT (0.47) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL22718654 | 0.82 | GAA (0.44) | LMNAMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230131501-A1 | THERAPEUTIC USES OF INHIBITORS OF THE RNA-BINDING PROTEIN HuR | UNIVERSITY OF KANSAS | 2023-04-27 | — | — | US | disclosed |
| US-20230131501-A1 | THERAPEUTIC USES OF INHIBITORS OF THE RNA-BINDING PROTEIN HuR | UNIVERSITY OF KANSAS | 2023-04-27 | — | — | US | disclosed |
| WO-2021202137-A1 | THERAPEUTIC USES OF INHIBITORS OF THE RNA-BINDING PROTEIN HUR | UNIVERSITY OF KANSAS (US) | 2021-10-07 | — | — | WO | disclosed |
| WO-2021202137-A1 | THERAPEUTIC USES OF INHIBITORS OF THE RNA-BINDING PROTEIN HUR | UNIVERSITY OF KANSAS (US) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230131501-A1 | THERAPEUTIC USES OF INHIBITORS OF THE RNA-BINDING PROTEIN HuR | HNRNPH1, ELAVL1, RBM3 | HDAC1 383/4885LMNA 1702/4885SMN1; SMN2 1062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.