Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 20/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 9/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17605847 | 0.91 | EP300 (0.43) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL22040127 | 0.91 | EP300 (0.43) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL17605850 | 0.91 | EP300 (0.43) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL17605859 | 0.83 | EP300 (0.42) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL23891583 | 0.83 | EP300 (0.46) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL22039485 | 0.82 | EP300 (0.45) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL22039750 | 0.82 | EP300 (0.45) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL23891536 | 0.81 | EP300 (0.44) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL23891679 | 0.81 | EP300 (0.44) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL22039701 | 0.80 | EP300 (0.42) | EP300CREBBPCYP3A4CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |