Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3404042 | 0.93 | CYP1A2 (0.38) | KDM4ELMNANPC1RAB9AALOX12 | |
| SCHEMBL3405751 | 0.86 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2TBXAS1CYP1A2 | |
| SCHEMBL6518862 | 0.80 | DAGLA (0.48) | HTTTBXAS1CES1FAAHDAGLA | |
| SCHEMBL4186060 | 0.80 | DAGLA (0.48) | HTTTBXAS1CES1FAAHDAGLA | |
| SCHEMBL2913100 | 0.80 | DAGLA (0.48) | HTTTBXAS1CES1FAAHDAGLA | |
| SCHEMBL31740471 | 0.80 | DAGLA (0.48) | HTTTBXAS1CES1FAAHDAGLA | |
| SCHEMBL2916184 | 0.80 | DAGLA (0.48) | HTTTBXAS1CES1FAAHDAGLA | |
| SCHEMBL28846272 | 0.80 | DAGLA (0.48) | HTTTBXAS1CES1FAAHDAGLA | |
| SCHEMBL10618776 | 0.80 | DAGLA (0.48) | HTTTBXAS1CES1FAAHDAGLA | |
| SCHEMBL1960318 | 0.80 | DAGLA (0.48) | HTTTBXAS1CES1FAAHDAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |