Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 17/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 9/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24350339 | 0.91 | EP300 (0.38) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL22039604 | 0.89 | EP300 (0.34) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL22039600 | 0.89 | EP300 (0.34) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL22039785 | 0.85 | EP300 (0.49) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL22040898 | 0.85 | EP300 (0.49) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL22039602 | 0.85 | EP300 (0.49) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL23891536 | 0.83 | EP300 (0.44) | EP300CREBBPGABRA1TMEM97SLC6A4 | |
| SCHEMBL23891679 | 0.83 | EP300 (0.44) | EP300CREBBPGABRA1TMEM97SLC6A4 | |
| SCHEMBL22040901 | 0.82 | EP300 (0.35) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL22040252 | 0.77 | EP300 (0.49) | EP300CREBBPGABRA1TMEM97DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |