Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.61 |
| ▸ | AXL | P30530 | 4/20 | 0.54 |
| ▸ | MERTK | Q12866 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14736596 | 0.91 | PIK3CD (0.75) | PIK3CDAXLMERTK | |
| SCHEMBL30590271 | 0.91 | PIK3CD (0.75) | PIK3CDAXLMERTK | |
| Trifluoroacetic Acid SCHEMBL14736514 | 0.86 | PIK3CD (0.68) | PIK3CDAXLMERTK | |
| SCHEMBL21909959 | 0.85 | PIK3CD (0.71) | PIK3CD | |
| SCHEMBL31367070 | 0.85 | PIK3CD (0.71) | PIK3CD | |
| SCHEMBL16005856 | 0.85 | PIK3CD (0.66) | PIK3CDAXLMERTK | |
| SCHEMBL14736394 | 0.84 | PIK3CD (0.77) | PIK3CDAXLMERTK | |
| SCHEMBL31367079 | 0.83 | PIK3CD (0.79) | PIK3CDAXLMERTK | |
| SCHEMBL14736051 | 0.82 | PIK3CD (0.79) | PIK3CDAXLMERTK | |
| SCHEMBL14736720 | 0.82 | PIK3CD (0.79) | PIK3CDAXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888657-A1 | HETEROCYCLYLAMINES AS PI3K INHIBITORS | Incyte Holdings Corporation (US) | 2021-10-06 | — | — | EP | disclosed |