Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23395514 | 0.88 | CYP3A4 (0.35) | MAPTMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL23893404 | 0.86 | MAPT (0.41) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL23395493 | 0.85 | SRD5A1 (0.32) | KLK7KDM4EHPGDALDH1A1HTT | |
| SCHEMBL23395676 | 0.85 | HDAC6 (0.42) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL23893464 | 0.83 | KLK7 (0.42) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL23395667 | 0.82 | KLK7 (0.44) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL23395530 | 0.82 | HDAC6 (0.40) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL23893526 | 0.82 | MEN1 (0.45) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL25897947 | 0.82 | KLK7 (0.41) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL25896587 | 0.81 | CYP1A2 (0.33) | CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |