Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757118 | 0.84 | FFAR4 (0.43) | HTR2ASLC6A4KCNH2TSHRMAPT | |
| SCHEMBL23898370 | 0.83 | HTR2A (0.41) | HTR2ASLC6A4TSHRMAPTHTT | |
| SCHEMBL14446351 | 0.79 | SMN1; SMN2 (0.44) | HTR2ASLC6A4KCNH2TSHRMAPT | |
| SCHEMBL23898318 | 0.79 | SLC6A4 (0.31) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL5478703 | 0.78 | SLC6A4 (0.49) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| SCHEMBL5478710 | 0.78 | SLC6A4 (0.49) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| SCHEMBL5478701 | 0.78 | SLC6A4 (0.49) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL5480005 | 0.77 | SLC6A4 (0.48) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL5480010 | 0.77 | SLC6A4 (0.48) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL5480001 | 0.77 | SLC6A4 (0.48) | HTR2ASLC6A4KCNH2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198149-A1 | SUBSTITUTED 3-PHENOXYAZETIDIN-1-YL-PYRAZINES HAVING GPR52 AGONISTIC ACTIVITY | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-10-07 | — | — | WO | disclosed |