Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20824798 | 0.89 | EGFR (0.51) | EGFR | |
| SCHEMBL29354186 | 0.86 | EGFR (0.50) | EGFR | |
| SCHEMBL18368428 | 0.86 | EGFR (0.50) | EGFR | |
| SCHEMBL29351103 | 0.86 | EGFR (0.50) | EGFR | |
| SCHEMBL18367741 | 0.86 | EGFR (0.50) | EGFR | |
| SCHEMBL22702221 | 0.86 | EGFR (0.56) | EGFR | |
| SCHEMBL28712287 | 0.82 | EGFR (0.53) | EGFR | |
| SCHEMBL23899156 | 0.82 | EGFR (0.56) | EGFR | |
| SCHEMBL18367742 | 0.81 | EGFR (0.47) | EGFR | |
| SCHEMBL29350158 | 0.81 | EGFR (0.47) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202688-A1 | PROCESS FOR PREPARING A COT INHIBITOR COMPOUND | GILEAD SCIENCES, INC. (US) | 2021-10-07 | — | — | WO | disclosed |