Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 9/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31251323 | 0.84 | GAA (0.53) | GAABRD4TP53MAPTL3MBTL1 | |
| SCHEMBL23899066 | 0.84 | GAA (0.53) | GAABRD4TP53MAPTL3MBTL1 | |
| Cyanide SCHEMBL25406275 | 0.75 | GAA (0.44) | GAABRD4TP53MAPTL3MBTL1 | |
| SCHEMBL13833580 | 0.74 | GAA (0.57) | GAABRD4TP53MAPTL3MBTL1 | |
| SCHEMBL8063482 | 0.73 | GAA (0.56) | GAABRD4TP53MAPTL3MBTL1 | |
| SCHEMBL5140683 | 0.73 | GAA (0.56) | GAABRD4TP53MAPTL3MBTL1 | |
| SCHEMBL8268239 | 0.73 | GAA (0.56) | GAABRD4TP53MAPTL3MBTL1 | |
| SCHEMBL30529453 | 0.73 | GAA (0.56) | GAABRD4TP53MAPTL3MBTL1 | |
| SCHEMBL15519326 | 0.73 | GAA (0.56) | GAABRD4TP53MAPTL3MBTL1 | |
| SCHEMBL28702896 | 0.73 | GAA (0.56) | GAABRD4TP53MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202688-A1 | PROCESS FOR PREPARING A COT INHIBITOR COMPOUND | GILEAD SCIENCES, INC. (US) | 2021-10-07 | — | — | WO | disclosed |