SCHEMBL23901020

SCHEMBL23901020

CN1CCN(CCNC(=O)Nc2nc3ccc(-c4cccc5[nH]ccc45)cc3s2)CC1

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 16/20 0.69
MCHR1 Q99705 1/20 0.46
LIMK1 P53667 1/20 0.44
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
MET P08581 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23901067 0.92 ABL1 (0.69) ABL1METCYP3A4
SCHEMBL23901014 0.88 ABL1 (0.70) ABL1ALDH1A1POLBMETCYP3A4
SCHEMBL23901129 0.82 ABL1 (1.00) ABL1ALDH1A1POLB
SCHEMBL23901009 0.80 ABL1 (0.72) ABL1METCYP3A4
SCHEMBL1651703 0.80 PIK3CG (0.60) ABL1ALDH1A1CYP3A4
SCHEMBL3715324 0.78 ABL1 (0.66) ABL1LIMK1ALDH1A1POLB
SCHEMBL23901131 0.78 ABL1 (0.67) ABL1METCYP3A4
SCHEMBL2799688 0.78 ABL1 (0.67) ABL1ALDH1A1POLBMETCYP3A4
SCHEMBL23901069 0.78 ABL1 (0.52) ABL1
SCHEMBL23901071 0.77 ABL1 (0.66) ABL1METCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021201576-A1 BENZOTHIAZOLE DERIVATIVE COMPOUND 주식회사 이노큐어테라퓨틱스 2021-10-07 WO disclosed