Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901679 | 0.90 | RAF1 (0.34) | CD38 | |
| SCHEMBL23901519 | 0.81 | KDM4E (0.42) | CD38 | |
| SCHEMBL25578833 | 0.80 | CD38 (0.41) | CD38 | |
| SCHEMBL25578820 | 0.80 | CD38 (0.41) | CD38 | |
| SCHEMBL19629454 | 0.80 | CD38 (0.41) | CD38 | |
| SCHEMBL21460989 | 0.80 | CD38 (0.40) | CD38 | |
| SCHEMBL19451990 | 0.80 | CD38 (0.40) | CD38 | |
| SCHEMBL19578987 | 0.79 | EPHX2 (0.40) | CD38 | |
| SCHEMBL17741225 | 0.79 | EPHX2 (0.40) | CD38 | |
| SCHEMBL19438251 | 0.79 | CD38 (0.47) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309661-A1 | IMIDAZO[1,5-a]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL - R&D INVESTMENTS, S.A. (PT) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309661-A1 | IMIDAZO[1,5-a]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | GBA1, GAA, GBA2 | CD38 849/4885TRPV1 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.