Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25442702 | 0.96 | EPHX1 (0.56) | HTTHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL25442226 | 0.87 | HPGD (0.55) | HTTHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL23903436 | 0.85 | HTT (0.72) | HTTHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL8590012 | 0.78 | HTT (0.52) | HTTHSD17B10HPGDKMT2ALMNA | |
| SCHEMBL8621310 | 0.78 | HTT (0.52) | HTTHSD17B10HPGDKMT2ALMNA | |
| SCHEMBL8389804 | 0.78 | HTT (0.52) | HTTHSD17B10HPGDKMT2ALMNA | |
| SCHEMBL20114371 | 0.78 | HPGD (0.41) | HPGDKMT2AMEN1LMNAEPHX1 | |
| SCHEMBL11872394 | 0.77 | HPGD (0.51) | HTTHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL12961644 | 0.77 | ACKR3 (0.60) | HTTHPGDKMT2ALMNAEPHX1 | |
| SCHEMBL25442229 | 0.76 | HPGD (0.70) | HTTHSD17B10HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021203016-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-07 | — | — | WO | disclosed |