Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.61 |
| ▸ | CNR2 | P34972 | 3/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25443467 | 0.86 | NPC1 (0.63) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL25443355 | 0.84 | CNR1 (0.58) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL23903504 | 0.83 | CNR1 (0.61) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL6435539 | 0.81 | CNR1 (0.67) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL23903534 | 0.80 | CNR1 (0.65) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL23903561 | 0.80 | CNR1 (0.53) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL6431976 | 0.79 | CNR1 (0.63) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL25442168 | 0.77 | CNR1 (0.75) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL6432059 | 0.77 | CNR1 (0.61) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL27426269 | 0.77 | CNR1 (0.61) | CNR1CNR2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021203016-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-07 | — | — | WO | disclosed |