SCHEMBL23903753

SCHEMBL23903753

CC(C)(C)C(C)(C)C(=O)CN

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GLRA1 P23415 1/20 0.35
SLC6A9 P48067 1/20 0.35
OR51E2 Q9H255 1/20 0.35
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451714 0.75
SCHEMBL2525941 0.73
SCHEMBL9642490 0.73
SCHEMBL12424406 0.73 TDP1 (0.37)
Hydrochloric Acid SCHEMBL782363 0.73
SCHEMBL18822178 0.71
SCHEMBL13554238 0.71 HMGCR (0.33)
Hydrochloric Acid SCHEMBL5280142 0.71
SCHEMBL25571968 0.70 GLRA1 (0.30) GLRA1SLC6A9OR51E2KDM4E
SCHEMBL28236301 0.69 GLRA1 (0.40) GLRA1SLC6A9OR51E2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174985-A1 MODIFIED PEPTIDE NUCLEIC ACID COMPOSITIONS NEUBASE THERAPEUTICS, INC. 2023-06-08 US disclosed
US-20210324012-A1 MODIFIED PEPTIDE NUCLEIC ACID COMPOSITIONS NEUBASE THERAPEUTICS, INC. 2021-10-21 US disclosed
US-20210309997-A1 MODIFIED PEPTIDE NUCLEIC ACID COMPOSITIONS NEUBASE THERAPEUTICS, INC. 2021-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210309997-A1 MODIFIED PEPTIDE NUCLEIC ACID COMPOSITIONS TARDBP, SARNP, SNRPE GLRA1 2143/4885SLC6A9 3526/4885OR51E2 3398/4885
US-20210324012-A1 MODIFIED PEPTIDE NUCLEIC ACID COMPOSITIONS TARDBP, SARNP, SNRPE GLRA1 2143/4885SLC6A9 3526/4885OR51E2 3398/4885
US-20230174985-A1 MODIFIED PEPTIDE NUCLEIC ACID COMPOSITIONS TARDBP, SARNP, SNRPE GLRA1 2143/4885SLC6A9 3526/4885OR51E2 3398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.