Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 10/20 | 0.73 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | PRNP | P04156 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878308 | 0.85 | CACNA2D1 (1.00) | CACNA2D1 | |
| SCHEMBL5471335 | 0.85 | CACNA2D1 (1.00) | CACNA2D1 | |
| SCHEMBL23883133 | 0.85 | CACNA2D1 (0.77) | CACNA2D1 | |
| SCHEMBL14986075 | 0.81 | USP2 (0.79) | CACNA2D1APPNPC1USP2PRNP | |
| SCHEMBL14983507 | 0.78 | CACNA2D1 (0.82) | CACNA2D1APPNPC1USP2PRNP | |
| SCHEMBL5468409 | 0.77 | CACNA2D1 (0.83) | CACNA2D1 | |
| SCHEMBL8288054 | 0.77 | CACNA2D1 (0.80) | CACNA2D1APPNPC1USP2PRNP | |
| SCHEMBL5471094 | 0.77 | CACNA2D1 (0.80) | CACNA2D1APPNPC1USP2PRNP | |
| SCHEMBL5468037 | 0.77 | CACNA2D1 (0.80) | CACNA2D1APPNPC1USP2PRNP | |
| SCHEMBL5473857 | 0.74 | CACNA2D1 (0.77) | CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202669-A2 | NUCLEOSIDE AND NUCLEOTIDE CONJUGATE COMPOUNDS AND USES THEREOF | REYOUNG CORPORATION (US) | 2021-10-07 | — | — | WO | disclosed |