Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25902174 | 0.84 | PDE4D (0.41) | EPHX2PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL30007194 | 0.84 | EPHX2 (0.40) | EPHX2PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL23904765 | 0.84 | EPHX2 (0.40) | EPHX2PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL29633602 | 0.83 | HSD17B10 (0.45) | EPHX2PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL23905892 | 0.81 | CNR2 (0.49) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL23904750 | 0.80 | EPHX2 (0.40) | EPHX2PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL30117191 | 0.79 | NOTUM (0.54) | EPHX2PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL23704079 | 0.79 | NOTUM (0.54) | EPHX2PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL5787161 | 0.79 | CA12 (0.54) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL23958621 | 0.79 | PDE4B (0.38) | EPHX2PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |