Sulfamate

Sulfamate

SCHEMBL2390500

C1=CC2=CC=C1C2.NS(=O)(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
TSHR P16473 1/20 0.42
NT5E P21589 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
GSK3A P49840 1/20 0.30
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfamide SCHEMBL19553743 0.89 CA1 (0.35) CA1CA2CA4CA6CA5A
Hydrazine SCHEMBL7408130 0.76
Sulfamate SCHEMBL11400 0.65
Sulfamate SCHEMBL2545884 0.65 CA1 (1.00) CA1CA2TSHRNT5ECA4
Sulfamate SCHEMBL285371 0.65
Tetrahydrofuran SCHEMBL28175371 0.63 TSHR (0.50) CA1CA2TSHRNT5ECA4
Cyclohexane SCHEMBL4186999 0.62 CA1 (0.73) CA1CA2TSHRNT5ECA4
Sulfamate SCHEMBL23498394 0.61
Sulfamate SCHEMBL20658932 0.61
Sulfamate SCHEMBL3237937 0.61 CA1 (0.89) CA1CA2TSHRNT5ECA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8026070-B2 Differential detection of multimeric and monomeric forms of multimer-forming polypeptides PEOPLEBIO, INC. (KR) 2011-09-27 US disclosed
US-20100009388-A1 DIFFERENTIAL DETECTION OF MULTIMERIC AND MONOMERIC FORMS OF MULTIMER-FORMING POLYPEPTIDES PEOPLEBIO, INC. (KR) 2010-01-14 US disclosed