Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905400 | 0.87 | HSD17B2 (0.49) | HSD17B2PDGFRBPDGFRADPP4NPC1 | |
| SCHEMBL23904824 | 0.85 | HSD17B2 (0.47) | HSD17B2PDGFRBPDGFRADPP4NPC1 | |
| SCHEMBL23905399 | 0.85 | HSD17B2 (0.47) | HSD17B2PDGFRBPDGFRALMNADPP4 | |
| SCHEMBL23904823 | 0.85 | HSD17B2 (0.47) | HSD17B2PDGFRBPDGFRADPP4NPC1 | |
| SCHEMBL23905885 | 0.84 | HSD17B2 (0.46) | HSD17B2PDGFRBPDGFRADPP4NPC1 | |
| SCHEMBL23905883 | 0.84 | HSD17B2 (0.46) | HSD17B2PDGFRBPDGFRALMNACYP1A2 | |
| SCHEMBL23905882 | 0.82 | HSD17B2 (0.45) | HSD17B2PDGFRBPDGFRADPP4NPC1 | |
| SCHEMBL23905356 | 0.82 | CA12 (0.47) | PDGFRBPDGFRALMNAMEN1KMT2A | |
| SCHEMBL25114964 | 0.81 | MAOB (0.45) | HSD17B2PDGFRBPDGFRANPC1MEN1 | |
| SCHEMBL23905553 | 0.78 | PDGFRB (0.49) | HSD17B2PDGFRBPDGFRADPP4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |