Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 20/20 | 0.74 |
| ▸ | PDGFRA | P16234 | 10/20 | 0.74 |
| ▸ | KIT | P10721 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132325 | 0.92 | PDGFRB (0.64) | PDGFRBPDGFRAKIT | |
| SCHEMBL2388345 | 0.91 | PDGFRB (0.74) | PDGFRBPDGFRAKIT | |
| SCHEMBL2388895 | 0.90 | PDGFRB (0.74) | PDGFRBPDGFRA | |
| SCHEMBL1131907 | 0.89 | PDGFRB (0.76) | PDGFRBPDGFRAKIT | |
| SCHEMBL1132499 | 0.89 | PDGFRB (0.75) | PDGFRBPDGFRAKIT | |
| SCHEMBL6709661 | 0.87 | PDGFRB (0.75) | PDGFRBPDGFRAKIT | |
| SCHEMBL2389482 | 0.86 | PDGFRB (0.58) | PDGFRBPDGFRAKIT | |
| SCHEMBL6710982 | 0.86 | PDGFRB (0.56) | PDGFRBPDGFRAKIT | |
| SCHEMBL1132420 | 0.86 | PDGFRB (0.73) | PDGFRBPDGFRAKIT | |
| SCHEMBL6709459 | 0.86 | PDGFRB (0.58) | PDGFRBPDGFRAKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022071-B2 | Nitrogenous heterocyclic compounds | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-20 | — | — | US | claimed |
| EP-1309568-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | Millennium Pharmaceuticals, Inc. (US) | 2003-05-14 | — | — | EP | claimed |
| WO-2002016361-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | COR THERAPEUTICS, INC. (US) | 2002-02-28 | — | — | WO | claimed |