Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23196094 | 0.92 | GRM2 (0.37) | CFTRGRM2RORCPDE3BPDE3A | |
| SCHEMBL23905474 | 0.92 | CFTR (0.35) | CFTRGRM2RORCPDE3BPDE3A | |
| SCHEMBL23904728 | 0.92 | CFTR (0.35) | CFTRGRM2RORCPDE3BPDE3A | |
| SCHEMBL24987101 | 0.91 | CFTR (0.37) | CFTRGRM2RORCPDE3BPDE3A | |
| SCHEMBL31412429 | 0.91 | GRM2 (0.37) | CFTRGRM2RORCPDE3BPDE3A | |
| SCHEMBL23905654 | 0.91 | CFTR (0.37) | CFTRGRM2RORCPDE3BPDE3A | |
| SCHEMBL24987997 | 0.91 | GRM2 (0.37) | CFTRGRM2RORCPDE3BPDE3A | |
| SCHEMBL24984865 | 0.90 | CFTR (0.38) | CFTRGRM2RORCPDE3BPDE3A | |
| SCHEMBL23905836 | 0.90 | GRM2 (0.35) | CFTRGRM2RORCPDE3BPDE3A | |
| SCHEMBL23905373 | 0.90 | GRM2 (0.35) | CFTRGRM2RORCPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |