Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | UBE2N | P61088 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24986770 | 0.95 | POLB (0.37) | POLBCFTRKMT2AMEN1LMNA | |
| SCHEMBL24986796 | 0.94 | POLB (0.37) | POLBCFTRKMT2AMEN1LMNA | |
| SCHEMBL24986069 | 0.92 | POLB (0.36) | POLBCFTRKMT2AMEN1LMNA | |
| SCHEMBL24986067 | 0.92 | POLB (0.36) | POLBCFTRKMT2AMEN1LMNA | |
| SCHEMBL24986078 | 0.92 | POLB (0.36) | POLBCFTRKMT2AMEN1LMNA | |
| SCHEMBL24986076 | 0.92 | POLB (0.36) | POLBCFTRKMT2AMEN1LMNA | |
| SCHEMBL24345459 | 0.92 | POLB (0.39) | POLBCFTRKMT2AMEN1LMNA | |
| SCHEMBL24986063 | 0.92 | POLB (0.36) | POLBCFTRKMT2AMEN1LMNA | |
| SCHEMBL24984500 | 0.92 | POLB (0.36) | POLBCFTRKMT2AMEN1LMNA | |
| SCHEMBL24345298 | 0.92 | POLB (0.37) | POLBCFTRKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |