Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905585 | 0.85 | ADORA2A (0.36) | ADORA1ADORA2AADORA2BBACE1 | |
| SCHEMBL23905810 | 0.85 | ADORA2A (0.36) | ADORA1ADORA2AADORA2BAPPBACE1 | |
| SCHEMBL23904736 | 0.85 | — | — | |
| SCHEMBL23904862 | 0.81 | — | — | |
| SCHEMBL23905774 | 0.81 | — | — | |
| SCHEMBL23904874 | 0.81 | CFTR (0.31) | — | |
| SCHEMBL23905611 | 0.80 | — | — | |
| SCHEMBL23905607 | 0.80 | KDM4E (0.33) | ADORA2A | |
| SCHEMBL23904873 | 0.80 | — | — | |
| SCHEMBL23905594 | 0.80 | HDAC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |