Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26159417 | 0.92 | CYP3A4 (0.38) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26160431 | 0.92 | CYP3A4 (0.38) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23905888 | 0.91 | CYP3A4 (0.40) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL32675616 | 0.91 | CYP3A4 (0.40) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26159400 | 0.91 | CYP3A4 (0.40) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23905941 | 0.91 | CYP3A4 (0.40) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26159402 | 0.91 | CYP3A4 (0.40) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23905904 | 0.91 | CYP3A4 (0.40) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26160352 | 0.91 | CYP3A4 (0.40) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26159403 | 0.91 | CYP3A4 (0.40) | CYP3A4MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |